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Mechanistic scientific tests revealed compound forty eight induced S-phase cell cycle arrest and apoptosis in CCRF-CEM cells. The construction–action relationship (SAR) Investigation indicated that a 5,six-dimethoxy moiety as well as a two-ethyl ester team about the indole scaffold were being important for very good antiproliferative potency, hig
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-indazoles 1a–m with different substituted aldehydes 2a–q/benzyl alcohols 5a–e/styrenes 6a–e in around 87% yields.Key phrases: indole; biological functions; anticancer; antimicrobial; anti-inflammatory; antidiabetic; neurodegenerative ailments; antihypertensiveYou presently know The easiest method to remedy UTI is with prescription cure—w